raloxifene may have further benefits in women on hemodialysis

Raloxifene May Have Further Benefits in Women on Hemodialysis

Saito et al. report on the possible beneficial effects of raloxifene on bone metabolism in women on hemodialysis (1). We commend the authors on their investigation of treatment in this difficult group. Currently there are limited options available for osteoporosis management in women on hemodialysis which is a significant concern given that the fracture rate for these women is quadruple that of...

raloxifene in hemodialysis patients

Effects of Raloxifene on Bone Metabolism in Hemodialysis Patients

Saito et al. (1) reported that raloxifene (RAL) suppressed bone turnover and increased the quantitative ultrasound (QUS) parameter, speed of sound (SOS) of the calcaneus in hemodialysis postmenopausal women with type 2 diabetes or without type 2 diabetes. Baseline bone turnover markers like serum cross-linked N-terminal telopeptides of type I collagen (NTX) and bone-specific alkaline phosphatas...

Significant Effect of Raloxifene on Bone in Hemodialysis Patients

Attention should be drawn to the study by colleagues Saito O et al. published in the International journal of Endocrinology and Metabolism (1). The study suggests that raloxifene has a significant beneficial effect on bone in postmenopausal women with type 2 diabetes (2DM) undergoing hemodialysis (1). Hemodialysis patients are known to have a high risk of low bone mineral density and bone fract...

Safety of Raloxifene in Hemodialysis Patients

With interest I read the article from Saito and colleagues about “the effects of raloxifene on bone metabolism in hemodialysis patients with type 2 diabetes” (1). The article addresses the possibility of treatment with raloxifene for osteoporosis in these patients. Raloxifene, a selective estrogen receptor modulator could be a good option, because it has no known renal side effects like bisphos...

Yoga May Have Health Benefits for People with Asthma

The Cochrane Library. The single most reliable source of evidence in healthcare The Cochrane Reviews highlighted below are available from the Cochrane Database of Systematic Reviews (www.thecochranelibrary.com) Cochrane Reviews are regularly updated as new evidence emerges and in response to feedback, and the Cochrane Database of Systematic Reviews should always be consulted for the most recent...